Management of Anaphylaxis

Algorithm reproduced with the kind permission of the Resuscitation Council (UK).

Other information

Anaphylaxis can be precipitated by a broad range of triggers which can include medicines, food, radio-opaque dyes and venom. On admission, known allergies must be clearly documented on the patient’s kardex and in the medical notes. Any new allergies identified must be documented and communicated to the patient and the patient’s GP. If a drug is the trigger then also complete a ‘Yellow card’ adverse drug reaction form. Forms can be found in the BNF or at

Follow the NICE Pathway "Anaphylaxis: assessment and referral after emergency treatment overview" available here, specifically:

  • All patients should be referred to a specialist clinic for allergy assessment.
  • Offer the patient (or, if appropriate, their parent and/or carer) an appropriate adrenaline auto-injector as an interim measure before the specialist allergy review (unless the reaction was drug-induced).
  • Individuals prescribed adrenaline auto-injectors must receive training in their use, and an emergency management or action plan.


 Guideline reviewed and content updated June 2021