Theophylline

Time to steady state: 2–3 days

Sampling time and target range

8-12 hours after dose (not critical): 10–20mg/L

Comment

Metabolised in the liver.

5-10mg/L may be adequate if patient is well controlled within this range.

For IV aminophylline dose and administration guidance see here.  

Guideline reviewed: August 2021

Page updated: March 2022