Tobramycin

Time to steady state: 1 day (longer in renal impairment).

Sampling time and target range

Trough (end of dose interval): <1mg/L

Peak (1 hour after dose): >10mg/L

or

6-14 hours post dose (if not CF) - use gentamicin plot in Gentamicin dosing guidelines

Comment

Use patient specific dose in cystic fibrosis (CF). Use gentamicin guidelines if patient specific dose is not available.

Guideline reviewed: August 2021

Page updated: March 2022