Thromboprophylaxis - low molecular weight heparin (LMWH) dose guide in renal impairment

For patients with very high or very low body weight, refer to separate GGC guidance available here.

Table 1: Prophylactic LMWH dosing

*GGC CrCl calculator available within the GGC Medicines App or on NHSGGC StaffNet / Clinical Info section (link only active if accessing in to GGC NHS account).

**If CrCl <30ml/minute and prophylactic LMWH treatment has continued for ≥10days, reassess anti-Xa activity after the 10th dose of LMWH, to ensure there has been no significant drug accumulation (target 4 hour peak level: 0.1-0.4units/ml).

Guideline reviewed: February 2021

Page last updated: September 2023