| Commence Variable Rate Intravenous Insulin Infusion (VRIII) for 24 hours |
| ↓ |
| To calculate Total Daily Dose (TDD):
Calculate total IV insulin used in 24 hour period and subtract 25% |
| ↓ |
|
1. Give 2/3 of TDD as Humulin® M3 at start of feed |
| ↓ |
| 2. Stop VRIII 2 hours after Humulin® M3 was administered |
| ↓ |
| 3. Give remaining 1/3 of TDD as Humulin® I at 12 hours into the feed |
| ↓ |
| Increase or decrease by 10-20% to reach target CBG (6-10mmol/L, unless otherwise specified) |
Guideline reviewed: February 2025
Page updated: November 2025
