GGC Medicines

Adult Therapeutics Handbook

Skin and soft tissue infections

Skin and soft tissue infections

Infection guidelines not covered by the NHSGGC Poster


  • Likely organisms are Streptococcus pyogenes and Staphylococcus aureus
  • Assess severity of infection and document in patient's notes the presence of:
    • Heat / erythema / induration / swelling (indicates severe infection if any 2 of these signs present).
    • Evidence of organ hypoperfusion, refer to Infection Management Guideline poster above for details. 
  • Microbiological sampling essential, send blood cultures, pus samples when present. Swab if wound is clinically infected or erythema, heat, induration observed. Do not swab wounds unless signs of infection or for MRSA screening.
  • Drain abscesses and debride necrotic tissue to achieve adequate source control.
  • Localised abscesses do not require antibiotics following incision and drainage.


Content last updated January 2021