Check the ward list for the patient's normal dose (Queen Elizabeth University Hospital) and check a peak (1 hour after dose) and a trough (end of dosage interval) at 48 hours of therapy. Tobramycin target peak is 8-12mg/L and trough is <1mg/L.
Or
for new CF patients, use the ward guidelines to calculate the initial dosage regimen. Sampling guidelines as above. Seek advice from pharmacy or microbiology if you are unsure how to interpret the result.
To calculate tobramycin dose, use the gentamicin dosing calculator on NHSGGC StaffNet / Clinical Info page (access to GGC Sharepoint needed) or the gentamicin dosing guideline.
Guideline reviewed: December 2023
Page update: December 2023
