Venous thromboembolism treatment - enoxaparin dosing if standard thrombosis risk
- Table 2 below is only for the management of patients who have a standard thrombosis risk:
- Uncomplicated DVT with low risk of recurrence.
- PE treatment beyond the acute period (e.g. nil-by-mouth after been established on oral anticoagulation).
- If the patient is at high risk of thrombosis - see table 3 for dosing advice.
- If the patient's renal function (creatinine clearance) is <30ml/minute - see table 4 for dosing advice.
Table 2 – Enoxaparin standard thrombosis risk dosing
| Actual weight (kg) |
Standard thrombosis risk dose 1.5mg/kg once daily |
| 35–44 |
60mg once daily |
| 45–59 |
80mg once daily |
| 60–73 |
100mg once daily |
| 74-88 |
120mg once daily |
| 89-110 |
150mg once daily |
| >110 |
Use high risk dosing |
|
NOTES
- If very low or high body weight (e.g. <35kg or >120kg), consider assessing anti-factor Xa activity after 3 consecutive doses to check dose is therapeutic, and after 8-10 doses to check for accumulation. The level should be taken 4 hours post-dose with a target of 0.5-1.2units/ml.
- GGC guidance on heparin dose adjustment for patients with high or low body weight is available on the Clinical Guideline Platform.
|
Guideline reviewed: July 2026
Page updated: July 2026
